DR4 抗体 (AA 401-468) (Alexa Fluor 350)
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- 抗原 See all DR4 抗体
- DR4 (Drought-Repressed 4 Protein (DR4))
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抗原表位
- AA 401-468
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DR4 antibody is conjugated to Alexa Fluor 350
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DR4
- 亚型
- IgG
- Top Product
- Discover our top product DR4 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DR4 (Drought-Repressed 4 Protein (DR4))
- 别名
- DR4 (DR4 产品)
- 别名
- APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNF receptor superfamily member 10a antibody, TNFRSF10A antibody
- 背景
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Synonyms: DR4, APO2, CD261, TRAILR1, TRAILR-1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, TNFRSF10A
Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
- 基因ID
- 8797
- UniProt
- O00220
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
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