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DR4 产品

(Drought-Repressed 4 Protein (DR4))

Categories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008].

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Featured DR4 Categories

DR4 抗体

High quality antibodies with extensive validation data.

Recommended DR4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN670581
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7214618
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN3184356
Quantity 100 μL
Datasheet Datasheet

Recommended DR4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN2566512
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN2566511
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our DR4 Products

Luo, Pan, Liu, Yuan, Yan: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).

Mizui, Yamazaki, Sagane, Tanaka: "cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter." in: Gene, Vol. 233, Issue 1-2, pp. 67-74, (1999) (PubMed).

Peschon, Slack, Reddy, Stocking, Sunnarborg, Lee, Russell, Castner, Johnson, Fitzner, Boyce, Nelson, Kozlosky, Wolfson, Rauch, Cerretti, Paxton, March, Black: "An essential role for ectodomain shedding in mammalian development." in: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1281-4, (1998) (PubMed).

Marsters, Sheridan, Donahue, Pitti, Gray, Goddard, Bauer, Ashkenazi: "Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B." in: Current biology : CB, Vol. 6, Issue 12, pp. 1669-76, (1997) (PubMed).

Bodmer, Burns, Schneider, Hofmann, Steiner, Thome, Bornand, Hahne, Schröter, Becker, Wilson, French, Browning, MacDonald, Tschopp: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, (1997) (PubMed).

Synonyms and alternative names related to DR4

TNF receptor superfamily member 10a (TNFRSF10A), APO2, CD261, DR4, TRAILR-1, TRAILR1

Protein level used designations for DR4

  • TNF-related apoptosis-inducing ligand receptor 1
  • TRAIL receptor 1
  • TRAIL-R1
  • cytotoxic TRAIL receptor
  • death receptor 4
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily member 10a variant 2
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