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Calpain 2 抗体 (AA 301-400) (Alexa Fluor 488)

CAPN2 适用: 人, 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN886195
发货至: 中国
  • 抗原 See all Calpain 2 (CAPN2) 抗体
    Calpain 2 (CAPN2)
    抗原表位
    • 14
    • 11
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    适用
    • 61
    • 36
    • 19
    • 5
    • 2
    • 1
    人, 小鼠
    宿主
    • 60
    • 6
    克隆类型
    • 51
    • 15
    多克隆
    标记
    • 30
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Calpain 2 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 41
    • 21
    • 14
    • 13
    • 13
    • 10
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse Calpain 2
    亚型
    IgG
    Top Product
    Discover our top product CAPN2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Calpain 2 (CAPN2)
    别名
    Calpain 2 (CAPN2 产品)
    别名
    CANP2 antibody, CANPL2 antibody, CANPml antibody, mCANP antibody, AI326419 antibody, Capa-2 antibody, Capa2 antibody, m-calpain antibody, m-calpin antibody, capn2 antibody, CAPN2 antibody, im:6908877 antibody, zgc:109906 antibody, calpain 2 antibody, calpain 2, gene2 antibody, calpain 2, (m/II) large subunit b antibody, CAPN2 antibody, Capn2 antibody, capn2.2 antibody, capn2b antibody
    背景

    Synonyms: Calcium activated neutral proteinase 2, Calcium activated neutral proteinase, CALP80, Calpain 2 m/II large subunit, Calpain 2 catalytic subunit, Calpain 2 large catalytic subunit, Calpain 2 large subunit, Calpain large polypeptide L2, Calpain M type, Calcium-activated neutral proteinase 2, CALP80, Calpain 2, large [catalytic] subunit, Calpain M-type, Calpain-2 catalytic subunit, Calpain-2 large subunit, CAN2_MOUSE, M-calpain, Millimolar-calpain, Calpain2, CANP 2, CANP L2, CANP2, CANPL 2, CANPL2, CANPml, Capa2, CAPN 2, CAPN2, FLJ39928, M calpain, M calpin, M type, mCANP, Millimolar calpain.

    Background: Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.

    基因ID
    824
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