Angiotensin II Type 2 Receptor 抗体 (Alexa Fluor 488)
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- 抗原 See all Angiotensin II Type 2 Receptor (AGTR2) 抗体
- Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Angiotensin II Type 2 Receptor antibody is conjugated to Alexa Fluor 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 兔, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse AT2R1
- 亚型
- IgG
- Top Product
- Discover our top product AGTR2 Primary Antibody
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anti-Angiotensin II Receptor, Type 2 (AGTR2) (AA 21-35), (Extracellular), (N-Term) antibody
AGTR2 适用: 小鼠, 大鼠 WB, IHC, ICC, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) antibodyAGTR2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) (Internal Region) antibodyAGTR2 适用: 人, 小鼠, 大鼠, Pig, Cow, 马, 犬, 猴, Hamster, 绵羊, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) (AA 21-35), (Extracellular), (N-Term) antibody (Atto 488)AGTR2 适用: 小鼠, 大鼠 IHC, ICC, IF, LCI 宿主: 兔 Polyclonal Atto 488
anti-Angiotensin II Receptor, Type 2 (AGTR2) antibodyAGTR2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) antibodyAGTR2 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 6C7 unconjugated Recombinant Antibody
anti-Angiotensin II Receptor, Type 2 (AGTR2) antibodyAGTR2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) (N-Term) antibodyAGTR2 适用: 人, 小鼠, Pig, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) (Internal Region) antibodyAGTR2 适用: 人, 小鼠, 大鼠, Pig, Cow, 马, 犬, 猴, Hamster, 绵羊, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 2 (AGTR2) (AA 250-350) antibodyAGTR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FCM(1:100-500)
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))
- 别名
- AT2R (AGTR2 产品)
- 别名
- AT2 antibody, ATGR2 antibody, MRX88 antibody, AI316812 antibody, AW107640 antibody, AT2-R antibody, AT2R antibody, AT2R antibody, at2 antibody, zgc:113016 antibody, AGTR2 antibody, angiotensin II receptor type 2 antibody, angiotensin II receptor, type 2 antibody, AGTR2 antibody, Agtr2 antibody, agtr2 antibody
- 背景
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Synonyms: AG2S, Agtr 1, Agtr1, AGTR1_HUMAN, Agtr1a, AGTR1B, Ang II, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, Angiotensin II type-1 receptor, Angiotensin receptor 1, Angiotensin receptor 1B, AT 1B, AT 1r, AT-1B, AT-1r, AT1, At1a, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R, Type 1 angiotensin II receptor, Type 1B angiotensin II receptor, Type-1 angiotensin II receptor.
Background: Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.
- 分子量
- 41kDa
- 基因ID
- 11607
- 途径
- ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones
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