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PRKAB1 抗体 (AA 201-272) (Alexa Fluor 488)

PRKAB1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN882505
发货至: 中国
  • 抗原 See all PRKAB1 抗体
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    抗原表位
    • 20
    • 17
    • 15
    • 15
    • 14
    • 10
    • 9
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-272
    适用
    • 114
    • 99
    • 96
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 136
    • 9
    克隆类型
    • 127
    • 18
    多克隆
    标记
    • 52
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    This PRKAB1 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 81
    • 64
    • 64
    • 47
    • 29
    • 21
    • 15
    • 15
    • 11
    • 7
    • 5
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human AMPK beta 2
    亚型
    IgG
    Top Product
    Discover our top product PRKAB1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    别名
    AMPK beta 1 (PRKAB1 产品)
    别名
    AMPK antibody, HAMPKb antibody, 1300015D22Rik antibody, AU021155 antibody, E430008F22 antibody, MGC82489 antibody, prkab1 antibody, wu:fk93d05 antibody, wu:fw87e09 antibody, zgc:56652 antibody, zgc:76975 antibody, zgc:92228 antibody, protein kinase AMP-activated non-catalytic subunit beta 1 antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a antibody, PRKAB1 antibody, Prkab1 antibody, prkab1.S antibody, prkab1 antibody, prkab1b antibody, prkab1a antibody
    背景

    Synonyms: AMP activated protein kinase beta 2 non catalytic subunit, AMPK beta 2, AMPK beta 2 chain, PRKAB 2, Protein kinase AMP activated beta 2 non catalytic subunit, PRKAB1, AMPK subunit beta-1, AMPKb

    Background: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.

    基因ID
    5565, 5564
    途径
    AMPK Signaling, Warburg Effect
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