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PRKAB1 抗体 (AA 4-34)

PRKAB1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032386
发货至: 中国
  • 抗原 See all PRKAB1 抗体
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    抗原表位
    • 20
    • 16
    • 15
    • 15
    • 15
    • 10
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4-34
    适用
    • 113
    • 100
    • 96
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 135
    • 9
    克隆类型
    • 127
    • 17
    多克隆
    标记
    • 50
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    This PRKAB1 antibody is un-conjugated
    应用范围
    • 79
    • 65
    • 65
    • 47
    • 27
    • 22
    • 15
    • 15
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    Expected species reactivity: Rat
    纯化方法
    Purified
    免疫原
    A portion of amino acids 4-34 from the human protein was used as the immunogen for this AMPK beta 1 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PRKAB1 Primary Antibody
  • 应用备注
    Titration of the AMPK beta 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the AMPK beta 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    别名
    AMPK beta 1 (PRKAB1) (PRKAB1 产品)
    别名
    AMPK antibody, HAMPKb antibody, 1300015D22Rik antibody, AU021155 antibody, E430008F22 antibody, MGC82489 antibody, prkab1 antibody, wu:fk93d05 antibody, wu:fw87e09 antibody, zgc:56652 antibody, zgc:76975 antibody, zgc:92228 antibody, protein kinase AMP-activated non-catalytic subunit beta 1 antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a antibody, PRKAB1 antibody, Prkab1 antibody, prkab1.S antibody, prkab1 antibody, prkab1b antibody, prkab1a antibody
    背景
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
    UniProt
    Q9Y478
    途径
    AMPK Signaling, Warburg Effect
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