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IL-1 beta 抗体 (AA 161-269)

This anti-IL-1 beta antibody is a 兔 多克隆 antibody detecting IL-1 beta in WB, ELISA, IF (p), IHC (p), IF (cc) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, 兔 和 Cow. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN872644
发货至: 中国

Quick Overview for IL-1 beta 抗体 (AA 161-269) (ABIN872644)

抗原

See all IL-1 beta (IL1B) 抗体
IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

适用

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人, 小鼠, 大鼠, 兔, Cow

宿主

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  • 129
  • 8
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  • 1

克隆类型

  • 227
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  • 2
多克隆

标记

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This IL-1 beta antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 26
    • 24
    • 15
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    • 14
    • 12
    • 11
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    • 7
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 161-269

    交叉反应

    Cow, 人, 小鼠, 兔, 大鼠

    预测反应

    Dog,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IL-1 Beta

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Zhou, Homberg, Fang, Wang, Li, Meng, Shen, Luan, Liao, Swaab, Shan, Liu: "Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model." in: Brain, behavior, and immunity, Vol. 76, pp. 61-73, (2019) (PubMed).

    Dinesh, Rasool et al.: "Berberine, an isoquinoline alkaloid suppresses TXNIP mediated NLRP3 inflammasome activation in MSU crystal stimulated RAW 264.7 macrophages through the upregulation of Nrf2 transcription factor and ..." in: International immunopharmacology, Vol. 44, pp. 26-37, (2017) (PubMed).

    Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: "CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells." in: Molecular and cellular biochemistry, Vol. 376, Issue 1-2, pp. 137-43, (2013) (PubMed).

  • 抗原

    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

    别名

    Il-1 beta

    背景

    Synonyms: IL-1, IL1F2, IL1-BETA, Interleukin-1 beta, IL-1 beta, Catabolin, IL1B

    Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

    基因ID

    3553

    UniProt

    P01584

    途径

    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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