The antibody detects endogenous levels of total C/EBPb protein.
纯化方法
Affinity purified
免疫原
Peptide sequence around AA 336-340 (E-P-L-L-A) derived from Human C, EBPb. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation