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p53 抗体
TP53
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
p53抗体详情
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抗原
See all p53 (TP53) 抗体
p53 (TP53)
(Tumor Protein P53 (TP53))
适用
All reactivities for p53 抗体
人
宿主
All hosts for p53 抗体
兔
克隆类型
All clonalities for p53 抗体
多克隆
标记
All conjugates for p53 抗体
This p53 antibody is un-conjugated
应用范围
All applications for p53 抗体
Western Blotting (WB)
特异性
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of p53.
交叉反应
人, 小鼠
产品特性
Positive Control: A431. Cellular Localization: Cytoplasm, nucleus
纯化方法
Immunogen affinity purified
亚型
IgG
Top Product
Discover our top product TP53 Primary Antibody
Alternatives
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anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53
适用: 人, 小鼠, 大鼠, 山羊
WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB: 1:500-1,000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.5mg/ml
缓冲液
1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
p53目标详情
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抗原
p53 (TP53)
(Tumor Protein P53 (TP53))
别名
p53 (TP53 产品 )
别名
BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
背景
P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. P53 is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is frequently mutated or inactivated in about 60% of cancers
分子量
~70kDa
UniProt
Q91XH8
途径
p53 Pathway , MAPK Pathway , PI3K-Akt Signaling , Apoptosis , AMPK Signaling , Chromatin Binding , ER-Nucleus Signaling , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Autophagy , Warburg Effect
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