CD41, CD61 抗体 (FITC)
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- 抗原 See all CD41, CD61 抗体
- CD41, CD61 (CD41,CD61)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD41, CD61 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- Ion Exchange or Affinity Chromatography.
- 免疫原
- Human platelets. Hybridization of Sp2/0-Ag14 myeloma cells with spleen cells from Balb/c mice.
- 克隆位点
- P2
- 亚型
- IgG1
- Top Product
- Discover our top product CD41, CD61 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.2 containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- This product is photosensitive and should be protected from light
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- 抗原
- CD41, CD61 (CD41,CD61)
- Abstract
- CD41, CD61 产品
- 背景
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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