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CD41, CD61 抗体 (PE)

适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PE
产品编号 ABIN7013957
发货至: 中国
  • 抗原 See all CD41, CD61 抗体
    CD41, CD61 (CD41,CD61)
    适用
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 20
    小鼠
    克隆类型
    • 20
    单克隆
    标记
    • 10
    • 4
    • 3
    • 2
    • 1
    This CD41, CD61 antibody is conjugated to PE
    应用范围
    • 16
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Human platelets
    克隆位点
    PAC-1
    亚型
    IgM kappa
    Top Product
    Discover our top product CD41, CD61 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    CD41, CD61 (CD41,CD61)
    别名
    CD41/CD61 (CD41, CD61 产品)
    背景
    CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa
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