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BMI1 抗体
BMI1
适用: 人
WB, ELISA
宿主: 小鼠
Monoclonal
unconjugated
BMI1抗体详情
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抗原
See all BMI1 抗体
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
适用
All reactivities for BMI1 抗体
人
宿主
All hosts for BMI1 抗体
小鼠
克隆类型
All clonalities for BMI1 抗体
单克隆
标记
All conjugates for BMI1 抗体
This BMI1 antibody is un-conjugated
应用范围
All applications for BMI1 抗体
Western Blotting (WB), ELISA
特异性
Nucleus
纯化方法
Protein G-Sepharose affinity purified
免疫原
Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.
亚型
IgG
Top Product
Discover our top product BMI1 Primary Antibody
Alternatives
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使用细节
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应用备注
Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
50µg/50µl
缓冲液
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
BMI1目标详情
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抗原
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
别名
Bmi1 (BMI1 产品 )
别名
FLVI2/BMI1 antibody, PCGF4 antibody, RNF51 antibody, AW546694 antibody, Bmi-1 antibody, Pcgf4 antibody, bmi1 antibody, pcgf4 antibody, psc1 antibody, wu:fb17g03 antibody, wu:fd18f06 antibody, BMI-1 antibody, pcgf4b antibody, bmi-1 antibody, bmi1-a antibody, bmi1-b antibody, bmi1b antibody, rnf51 antibody, xbmi-1 antibody, BMI1 proto-oncogene, polycomb ring finger antibody, BMI1 polycomb ring finger oncogene antibody, Bmi1 polycomb ring finger oncogene antibody, bmi1 polycomb ring finger oncogene 1a antibody, bmi1 polycomb ring finger oncogene 1b antibody, BMI1 proto-oncogene, polycomb ring finger L homeolog antibody, BMI1 antibody, LOC100230513 antibody, Bmi1 antibody, bmi1a antibody, bmi1b antibody, bmi1.L antibody
背景
The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
分子量
37kDa
NCBI登录号
NM_005180
途径
Cell Division Cycle , Autophagy
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