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BMI1 抗体

BMI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN781173
发货至: 中国
  • 抗原 See all BMI1 抗体
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    适用
    • 110
    • 47
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    • 1
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    宿主
    • 77
    • 31
    • 6
    小鼠
    克隆类型
    • 78
    • 36
    单克隆
    标记
    • 77
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    • 8
    • 5
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    This BMI1 antibody is un-conjugated
    应用范围
    • 91
    • 49
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    • 11
    • 5
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    Western Blotting (WB), ELISA
    特异性
    Nucleus
    纯化方法
    Protein G-Sepharose affinity purified
    免疫原
    Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.
    亚型
    IgG
    Top Product
    Discover our top product BMI1 Primary Antibody
  • 应用备注
    Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    50µg/50µl
    缓冲液
    0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    别名
    Bmi1 (BMI1 产品)
    别名
    FLVI2/BMI1 antibody, PCGF4 antibody, RNF51 antibody, AW546694 antibody, Bmi-1 antibody, Pcgf4 antibody, bmi1 antibody, pcgf4 antibody, psc1 antibody, wu:fb17g03 antibody, wu:fd18f06 antibody, BMI-1 antibody, pcgf4b antibody, bmi-1 antibody, bmi1-a antibody, bmi1-b antibody, bmi1b antibody, rnf51 antibody, xbmi-1 antibody, BMI1 proto-oncogene, polycomb ring finger antibody, BMI1 polycomb ring finger oncogene antibody, Bmi1 polycomb ring finger oncogene antibody, bmi1 polycomb ring finger oncogene 1a antibody, bmi1 polycomb ring finger oncogene 1b antibody, BMI1 proto-oncogene, polycomb ring finger L homeolog antibody, BMI1 antibody, LOC100230513 antibody, Bmi1 antibody, bmi1a antibody, bmi1b antibody, bmi1.L antibody
    背景
    The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
    分子量
    37kDa
    NCBI登录号
    NM_005180
    途径
    Cell Division Cycle, Autophagy
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