XPC 抗体 (AA 395-445)
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Quick Overview for XPC 抗体 (AA 395-445) (ABIN8125779)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 395-445
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原理
- XPC Antibody
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特异性
- This antibody detects endogenous levels of XPC at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human XPC AA range: 395-445
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC
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背景
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Background: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009],
Gene Name: XPC XPCC
Protein Name: XPC
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基因ID
- 7508
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UniProt
- Q01831
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途径
- p53 Pathway, DNA Damage Repair
抗原
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