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XPC 抗体 (N-Term)

XPC 适用: 人 WB 宿主: 兔 Polyclonal RB40964 unconjugated
产品编号 ABIN1882000
发货至: 中国
  • 抗原 See all XPC 抗体
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    抗原表位
    • 13
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 154-183, N-Term
    适用
    • 45
    • 3
    • 3
    • 1
    宿主
    • 44
    • 5
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XPC antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 10
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.
    克隆位点
    RB40964
    亚型
    Ig Fraction
    Top Product
    Discover our top product XPC Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Stern, Lin, Figueroa, Kelsey, Kiltie, Yuan, Matullo, Fletcher, Benhamou, Taylor, Placidi, Zhang, Steineck, Rothman, Kogevinas, Silverman, Malats, Chanock, Wu, Karagas: "Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer." in: Cancer research, Vol. 69, Issue 17, pp. 6857-64, (2009) (PubMed).

  • 抗原
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    别名
    XPC (XPC 产品)
    别名
    RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody
    背景
    This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
    分子量
    105953
    NCBI登录号
    NP_001139241, NP_004619
    UniProt
    Q01831
    途径
    p53 Pathway, DNA Damage Repair
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