ERK2 抗体 (N-Term) (APC)
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Quick Overview for ERK2 抗体 (N-Term) (APC) (ABIN8010879)
抗原
See all ERK2 (MAPK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-MAPK1/3 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MAPK1/3, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibody
MAPK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 25-360) antibodyMAPK1 适用: 人 WB, IHC, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 261-360) antibodyMAPK1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9H1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IP, FACS, IHC (p) 宿主: 小鼠 Monoclonal 6F8 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibodyMAPK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 25-360) antibodyMAPK1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 316-345), (C-Term) antibodyMAPK1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB11608 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 小鼠, 猴 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C11 unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
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别名
- MAPK1
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背景
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Background: MAPK1 (ERK2) shares high homology with MAPK3 (ERK1). MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Mitogen-activated protein (MAP) kinases [also known as Erks] have been established to function as important mediators of signal transduction by growth factor receptors. ERK1/ERK2-dependent activation of endogenous ribosomal transcription, while inactivation of ERK1/ERK2 causes an equally immediate reversion to the basal transcription level. ERK1/ERK2 was found to phosphorylate the architectural transcription factor UBF at amino acids 117 and 201 within HMG boxes 1 and 2, preventing their interaction with DNA. Mutation of these sites inhibited transcription activation and abrogated the transcriptional response to ERK1/ERK2.
Gene Full Name: mitogen-activated protein kinase 1
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
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基因ID
- 5594
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UniProt
- P28482
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins
抗原
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