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ERK2 抗体 (AA 200-300)

Name: ERK2 抗体 (AA 200-300)
Brand: antibodies-online
SKU: ABIN3020728
Availability: OutOfStock

MAPK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from normal (control) and ERK2 knockout (KO) HeLa cells, using ERK2 antibody (ABIN3020727, ABIN3020728, ABIN3020729 and ABIN6213694) at 1:1000 dilution. (ERK2 抗体 (AA 200-300))

Immunofluorescence analysis of A549 cell using ERK1/2 antibody. (ERK2 抗体 (AA 200-300))

Western blot analysis of extracts of various cell lines, using ERK1/2 antibody. (ERK2 抗体 (AA 200-300))

Western blot analysis of extracts of various cell lines, using MAPK1 antibody. (ERK2 抗体 (AA 200-300))

Regulation of VEGF in osteoblasts by mTORC1 does not explain the vascular phenotypes of mutant mouse bone. (ERK2 抗体 (AA 200-300))

Cxcl9 is responsible for vascular phenotypes in mutant mouse bone. (ERK2 抗体 (AA 200-300))

Cxcl9 antagonizes VEGF signalling transduction in ECs by interacting with VEGF and preventing its binding to ECs. (ERK2 抗体 (AA 200-300))

CRAMP reduces cardiomyocyte apoptosis via activating Akt and ERK1/2. (ERK2 抗体 (AA 200-300))

CRAMP reduces cardiac I/R injury in vivo. (ERK2 抗体 (AA 200-300))

9 images

(6 references)

产品编号 ABIN3020728

发货至: 中国

Datasheet as PDF

抗原 See all ERK2 (MAPK1) 抗体

ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
抗原表位
16

11

9

8

7

6

6

5

5

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 200-300
适用
131

70

67

13

9

7

7

6

5

5

4

4

3

2

2
人
宿主
96

33

4

3

1
兔
Compatible Secondaries
克隆类型
87

51
多克隆
标记
86

11

9

5

3

2

2

2

2

2

2

2

2

2

2

2

1

1
This ERK2 antibody is un-conjugated
应用范围
100

65

40

29

24

22

13

9

6

2

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF)

序列

LNSKGYTKSI DIWSVGCILA EMLSNRPIFP GKHYLDQLNH ILGILGSPSQ EDLNCIINLK ARNYLLSLPH KNKVPWNRLF PNADSKALDL LDKMLTFNPH K

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_620407.1).

亚型

IgG
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 25-360) antibody
MAPK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 261-360) antibody
MAPK1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1D1 unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody
MAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 6F8 unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody
MAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody
MAPK1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 9E9 unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibody
MAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9H1 unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibody
MAPK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (N-Term) antibody
MAPK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 310-360) antibody
MAPK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 25-360) antibody
MAPK1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

应用备注

WB,1:500 - 1:2000,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Huang, Wang, Li, Wang, Yan, Zhang, Wang, Huang, Jia, Lu, Liu, Chen, Li, Cai, Jiang, Jin, Bai: "Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone." in: Nature communications, Vol. 7, pp. 13885, (2018) (PubMed).

Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).

Li, Liu, Xie, Gu, Dai, Yao, Zhou: "Serum Exosomes Attenuate H2O2-Induced Apoptosis in Rat H9C2 Cardiomyocytes via ERK1/2." in: Journal of cardiovascular translational research, (2018) (PubMed).

Chaudhari, Talwar, Lefebvre Dhellencourt, Ravanan: "CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells." in: Frontiers in molecular neuroscience, Vol. 10, pp. 310, (2017) (PubMed).

Li, Yu, Wang, Xu, Chi, Qin, Liu: "The ω-carboxyl group of 7-ketocholesteryl-9-carboxynonanoate mediates the binding of oxLDL to CD36 receptor and enhances caveolin-1 expression in macrophages." in: The international journal of biochemistry & cell biology, Vol. 90, pp. 121-135, (2017) (PubMed).
抗原

ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

别名

MAPK1 (MAPK1 产品)

别名

ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, 9030612K14Rik antibody, AA407128 antibody, AU018647 antibody, C78273 antibody, Erk2 antibody, Prkm1 antibody, p42mapk antibody, zERK2 antibody, MAPK1 antibody, Xp42 antibody, erk antibody, erk2 antibody, ert1 antibody, mapk antibody, mapk1b antibody, mapk2 antibody, mpk1 antibody, prkm1 antibody, prkm2 antibody, mapk1 antibody, mapk1a antibody, xp42 antibody, ATMPK1 antibody, F14N23.9 antibody, F14N23_9 antibody, MITOGEN-ACTIVATED PROTEIN KINASE antibody, mitogen-activated protein kinase 1 antibody, MNK1 antibody, ATMPK2 antibody, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antibody, T30E16.13 antibody, T30E16_13 antibody, mitogen-activated protein kinase homolog 2 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 1 antibody, mitogen activated protein kinase 1 antibody, mitogen-activated protein kinase 1 L homeolog antibody, mitogen-activated protein kinase 1 S homeolog antibody, mitogen activated protein kinase 3 antibody, mitogen-activated protein kinase homolog 2 antibody, MAPK3 antibody, Mapk3 antibody, MAPK1 antibody, Mapk1 antibody, mapk1 antibody, mapk1.L antibody, mapk1.S antibody, PfMAP1 antibody, MPK1 antibody, PVX_084965 antibody, LOC9328617 antibody, Tsp_01601 antibody, MPK2 antibody

背景

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.,ERK,ERK-2,ERK2,ERT1,MAPK2,P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,p42-MAPK,MAPK1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centromere,Microtubules,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Stem Cells,Cardiovascular,Angiogenesis,MAPK1

分子量

36 kDa/41 kDa

基因ID

5594

UniProt

P28482

途径

MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins