XPC 抗体 (AA 146-838)
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Quick Overview for XPC 抗体 (AA 146-838) (ABIN7870736)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 146-838
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原理
- XPC Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids D146-E838) was used as the immunogen for the XPC antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the XPC antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the XPC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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别名
- XPC
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背景
- Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene. The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- Q01831
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途径
- p53 Pathway, DNA Damage Repair
抗原
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