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CHEK1 抗体

This anti-CHEK1 antibody is a 小鼠 单克隆 antibody detecting CHEK1 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7467901
发货至: 中国

Quick Overview for CHEK1 抗体 (ABIN7467901)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

6F5
  • 特异性

    Human Chk1

    交叉反应

    纯化方法

    Protein G affinity purified

    免疫原

    Full-length human Chk1

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    checkpoint kinase 1

    背景

    Checkpoint kinase 1 , CHK1,The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]

    分子量

    54 kDa

    基因ID

    1111

    UniProt

    O14757

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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