IL-1 beta 抗体
Quick Overview for IL-1 beta 抗体 (ABIN7490561)
抗原
See all IL-1 beta (IL1B) 抗体片段
适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Rabbit/Human Fc chimeric IgG1
-
纯化方法
- Purified from cell culture supernatant by affinity chromatography
-
亚型
- IgG1
-
-
anti-Interleukin 1, beta (IL1B) (AA 101-200) antibody
IL1B 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) antibodyIL1B 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A6 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 161-269) antibodyIL1B 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) (AA 170-269) antibodyIL1B 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 117-269) antibodyIL1B 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F12D5 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 117-269) antibodyIL1B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5C3B7 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 1-266) antibodyIL1B 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) (AA 1-269) antibodyIL1B 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1, beta (IL1B) (AA 148-174) antibodyIL1B 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21917 unconjugated
anti-Interleukin 1, beta (IL1B) (AA 148-174) antibodyIL1B 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cyt 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
-
别名
- IL1B
-
背景
-
IL-1, IL1-BETA, IL1F2,
Description: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Similarly, IL-1B has been implicated in human osteoarthritis pathogenesis. Patients with severe Coronavirus Disease 2019 (COVID-19) present elevated levels of pro-inflammatory cytokines such as IL-1B in bronchial alveolar lavage fluid samples. The lung damage induced by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL-1B. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. -
UniProt
- P01584
-
途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
-
