ERK2 抗体 (AA 310-360)
Quick Overview for ERK2 抗体 (AA 310-360) (ABIN7454543)
抗原
See all ERK2 (MAPK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-360
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原理
- Rabbit anti-ERK2 Antibody, Affinity Purified
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预测反应
- Rat,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 310 and 360
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
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别名
- ERK2
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背景
- Background: Extracellular signal-regulated kinase 2 (ERK2/p42) is also known as mitogen-activated protein kinase 1 (MAPK1). ERK2 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK2 is very similar in sequence to ERK1/p44 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.
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基因ID
- 5594
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NCBI登录号
- NP_002736
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UniProt
- P28482
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins
抗原
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