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CHEK1 抗体 (AA 250-300)

This anti-CHEK1 antibody is a 兔 多克隆 antibody detecting CHEK1 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7453553
发货至: 中国

Quick Overview for CHEK1 抗体 (AA 250-300) (ABIN7453553)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 250-300

    原理

    Rabbit anti-Chk1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 250 and 300

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    Chk1

    背景

    Background: Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.

    基因ID

    1111

    NCBI登录号

    NP_001265

    UniProt

    O14757

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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