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p53 抗体 (AA 325-375)

The 兔多克隆 anti-p53 antibody is suitable to detect p53 in samples from 人. It has been validated for WB 和 IP.

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产品编号 ABIN7450532

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

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Quick Overview for p53 抗体 (AA 325-375) (ABIN7450532)

抗原

See all p53 (TP53) 抗体

p53 (TP53) (Tumor Protein P53 (TP53))

适用

1052
341
270
140
75
74
54
37
11
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3
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1
1
1

人

宿主

兔

克隆类型

多克隆

标记

This p53 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunoprecipitation (IP)

Discover our top product TP53 Primary Antibody

抗原表位
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39

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3
AA 325-375

原理

Rabbit anti-p53 Antibody, Affinity Purified

纯化方法

Affinity Purified

免疫原

between AA 325 and 375

亚型

IgG
anti-Tumor Protein P53 (TP53) (pSer392) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) antibody
KO Validated TP53 适用: 人 WB, IF, IHC (p), IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (N-Term) antibody
TP53 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 适用: 人 WB, ELISA, IHC (p), PLA, RNAi 宿主: 小鼠 Monoclonal 2C11 unconjugated

anti-Tumor Protein P53 (TP53) (pSer20) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (acLys319) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (pSer15) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) antibody
TP53 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000

限制

仅限研究用
浓度

1000 μg/mL

缓冲液

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

有效期

12 months
抗原

p53 (TP53) (Tumor Protein P53 (TP53))

别名

p53

背景

Background: p53 is a tumor suppressor protein that is mutated or inactivated in over 50 % of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis.

基因ID

7157

NCBI登录号

NP_000537

UniProt

P04637

途径

p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect