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p53 抗体 (AA 50-100)

This 兔 多克隆 antibody specifically detects p53 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7448707
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for p53 抗体 (AA 50-100) (ABIN7448707)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

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宿主

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克隆类型

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多克隆

标记

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This p53 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 50-100

    原理

    Rabbit anti-p53 IHC Antibody, Affinity Purified

    预测反应

    Gorilla,Chimpanzee,Common tree shrew

    纯化方法

    Affinity Purified

    免疫原

    Between AA 50 and 100

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53

    背景

    Background: p53 is a tumor suppressor protein that is mutated or inactivated in over 50 % of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis.

    基因ID

    7157

    NCBI登录号

    NP_000537

    UniProt

    P04637

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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