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PEN2 抗体

PSENEN 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7269513
发货至: 中国
  • 抗原 See all PEN2 (PSENEN) 抗体
    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
    适用
    • 34
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    • 26
    • 5
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    • 2
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    • 1
    宿主
    • 38
    • 3
    克隆类型
    • 30
    • 11
    单克隆
    标记
    • 17
    • 3
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    • 2
    • 2
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    • 2
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    This PEN2 antibody is un-conjugated
    应用范围
    • 29
    • 14
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    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    PEN2/PSENEN Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human PEN2/PSENEN
    亚型
    IgG
    Top Product
    Discover our top product PSENEN Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
    别名
    PSENEN (PSENEN 产品)
    别名
    MSTP064 antibody, PEN-2 antibody, PEN2 antibody, Psenen antibody, ACYPI006208 antibody, 1700023M09Rik antibody, Pen-2 antibody, RGD1312037 antibody, CG33198 antibody, Dmel\\CG33198 antibody, anon-AE003800.1 antibody, dPen-2 antibody, psenen antibody, pen-2 antibody, pen2 antibody, zgc:109727 antibody, presenilin enhancer gamma-secretase subunit antibody, presenilin enhancer 2 antibody, presenilin enhancer gamma secretase subunit antibody, Gamma-secretase subunit pen-2 antibody, presenilin enhancer antibody, presenilin enhancer gamma secretase subunit S homeolog antibody, PSENEN antibody, PEN2 antibody, Psenen antibody, pen-2 antibody, psenen.S antibody, psenen antibody
    背景
    Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],MDS033, MSTP064, PEN-2, PEN2,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Notch Signaling Pathway,Signal Transduction,PSENEN
    分子量
    13kDa
    基因ID
    55851
    UniProt
    Q9NZ42
    途径
    Notch Signaling, Neurotrophin Signaling Pathway
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