PEN2 抗体 (C-Term)
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北京 101111
Quick Overview for PEN2 抗体 (C-Term) (ABIN2788066)
抗原
See all PEN2 (PSENEN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PSENEN Antibody - C-terminal region
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序列
- SQIKGYVWRS AVGFLFWVIV LTSWITIFQI YRPRWGALGD YLSFTIPLGT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PSENEN. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PSENEN
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anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 6-80) antibody
PSENEN 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 39-57) antibodyPSENEN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-101) antibodyPSENEN 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C12-G5 unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 斑马鱼, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 20-69) antibodyPSENEN 适用: 人, 小鼠, 犬, 马, 豚鼠, 兔, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (Internal Region) antibodyPSENEN 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-50) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59439-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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别名
- PSENEN
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背景
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Targeted Subunit: PEN-2
Background Information: Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Gene Name: Presenilin enhancer 2 homolog (C. elegans)
Alternative Symbols: PEN2, PEN-2, MDS033, ACNINV2, MSTP064
Protein Name: Gamma-secretase subunit PEN-2
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分子量
- 12kDa
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基因ID
- 55851
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NCBI登录号
- NP_758844
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UniProt
- Q9NZ42
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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