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PEN2 抗体 (C-Term)

This 兔 单克隆 antibody specifically detects PEN2 in WB, IF (cc), IF (p), FACS 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN6944688
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for PEN2 抗体 (C-Term) (ABIN6944688)

抗原

See all PEN2 (PSENEN) 抗体
PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

适用

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宿主

  • 50
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克隆类型

  • 31
  • 22
单克隆

标记

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This PEN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1D8
  • 抗原表位

    • 15
    • 4
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    • 1
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    C-Term

    原理

    PSENEN (1D8) Monoclonal Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide corresponding to C-terminal human PEN2.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

    别名

    PSENEN

    背景

    Synonyms: Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN, PEN2, presenilin enhancer gamma-secretase subunit, MDS033

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

    基因ID

    55851

    UniProt

    Q9NZ42

    途径

    Notch Signaling, Neurotrophin Signaling Pathway
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