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Phospholipase C gamma 1 抗体 (pSer1248)

PLCG1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269347
发货至: 中国
  • 抗原 See all Phospholipase C gamma 1 (PLCG1) 抗体
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    抗原表位
    • 40
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    pSer1248
    适用
    • 151
    • 137
    • 127
    • 23
    • 9
    • 6
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    • 3
    • 1
    • 1
    • 1
    宿主
    • 160
    • 23
    克隆类型
    • 144
    • 39
    多克隆
    标记
    • 86
    • 11
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    • 9
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    • 5
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    • 3
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    This Phospholipase C gamma 1 antibody is un-conjugated
    应用范围
    • 121
    • 53
    • 38
    • 30
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    • 27
    • 19
    • 17
    • 15
    • 13
    • 7
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    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Phospho-PLC gamma 1 (PLCG1)-S1248 Rabbit pAb
    序列
    REGSF
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic phosphorylated peptide around S1248 of human PLC gamma 1 (PLCG1) (NP_002651.2).
    亚型
    IgG
    Top Product
    Discover our top product PLCG1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:10 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    别名
    PLCG1 (PLCG1 产品)
    别名
    NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody
    背景
    The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.,PLCG1,NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1,Cancer,Signal Transduction,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,Protein phosphorylation,PLCG1
    分子量
    148kDa
    基因ID
    5335
    UniProt
    P19174
    途径
    RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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