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FGFR3 抗体

This anti-FGFR3 antibody is a 兔 单克隆 antibody detecting FGFR3 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7267191
发货至: 中国

Quick Overview for FGFR3 抗体 (ABIN7267191)

抗原

See all FGFR3 抗体
FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

适用

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宿主

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克隆类型

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单克隆

标记

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This FGFR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    FGFR3 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human FGFR3

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

    别名

    FGFR3

    背景

    This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009],ACH,CD333,CEK2,HSFGFR3EX,JTK4,FGFR3,Angiogenesis,Cancer,Cardiovascular,CDs,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Growth factors,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Neural Stem Cells,Signal Transduction,Stem Cells,FGFR3

    分子量

    98kDa

    基因ID

    2261

    UniProt

    P22607

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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