ABCB11 抗体
-
- 抗原 See all ABCB11 抗体
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This ABCB11 antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC)
- 原理
- Anti-BSEP Mouse Monoclonal Antibody
- 特异性
- Human BSEP. Reactivity with other species has not been investigated.
- 交叉反应
- 人
- 免疫原
- Recombinant human BSEP.
- 克隆位点
- G518-1
- 亚型
- IgG1
- Top Product
- Discover our top product ABCB11 Primary Antibody
-
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 21-120) antibody
ABCB11 适用: 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 421-663) antibodyABCB11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 600-750) antibodyABCB11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (Internal Region) antibodyABCB11 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) antibodyABCB11 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) antibodyABCB11 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 420-656) antibodyABCB11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) antibodyABCB11 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 705-718) antibodyABCB11 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 1038-1067), (C-Term) antibodyABCB11 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2211 unconjugated
-
- 应用备注
-
Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
- 浓度
- Lot specific
- 缓冲液
- Tris buffer, pH 7.3-7.7, 1 % BSA, 0.1 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
-
- 抗原
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
- 别名
- ABCB11 (ABCB11 产品)
- 别名
- ABCB11 antibody, Bsep antibody, ABC16 antibody, BRIC2 antibody, BSEP antibody, PFIC-2 antibody, PFIC2 antibody, PGY4 antibody, SPGP antibody, Lith1 antibody, BSEP/SPGP antibody, Spgp antibody, ATP binding cassette subfamily B member 11 antibody, bile salt export pump antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 11 antibody, ABCB11 antibody, LOC100489744 antibody, LOC100565276 antibody, EDI_111220 antibody, EDI_272930 antibody, abcb11 antibody, Abcb11 antibody
- 背景
- Bile salt export pump,Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner (PubMed:16332456, PubMed:22262466, PubMed:15791618, PubMed:18985798, PubMed:19228692, PubMed:20398791, PubMed:24711118, PubMed:29507376, PubMed:20010382, PubMed:32203132). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456). Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion (PubMed:15901796, PubMed:18245269). {PubMed:15791618, PubMed:15901796, PubMed:16332456, PubMed:18245269, PubMed:18985798, PubMed:19228692, PubMed:20010382, PubMed:20398791, PubMed:22262466, PubMed:24711118, PubMed:29507376, PubMed:32203132}.,Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette transporters which mediate the transport of bile acid, taurocholate, and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene appears to increase the risk of hepatocellular carcinoma in early life.,Apical cell membrane, Recycling endosome membrane, Endosome, Cell membrane,ATP-binding cassette sub-family B member 11
- UniProt
- O95342
-
