ABCB11 抗体 (C-Term)
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Quick Overview for ABCB11 抗体 (C-Term) (ABIN390059)
抗原
See all ABCB11 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1038-1067, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ABCB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1038-1067 amino acids from the C-terminal region of human ABCB11.
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亚型
- Ig Fraction
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 21-120) antibody
ABCB11 适用: 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 421-663) antibodyABCB11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 600-750) antibodyABCB11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (Internal Region) antibodyABCB11 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 1175-1199), (C-Term) antibodyABCB11 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) antibodyABCB11 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 420-656) antibodyABCB11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) antibodyABCB11 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) antibodyABCB11 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 705-718) antibodyABCB11 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
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有效期
- 6 months
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: "Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress." in: Nature medicine, Vol. 14, Issue 8, pp. 828-36, (2008) (PubMed).
: ""Do-not-resuscitate" orders during anesthesia and surgery." in: Anesthesiology, Vol. 74, Issue 3, pp. 606-8, (1991) (PubMed).
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: "Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress." in: Nature medicine, Vol. 14, Issue 8, pp. 828-36, (2008) (PubMed).
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- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
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别名
- ABCB11
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背景
- ABCB11 is involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. It is expressed predominatly, if not exclusively, in the liver, where it is further localized to the canilicular microvilli and to subcanilicular vesicles fo the hepatocytes. Structurally, ABCB11 is a multifunctional polypeptide with two homologus halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain. Defects in ABCB11 are the cause of progressive familial intrahepatic cholestasis 2 (PFIC2). PFIC2 is an inherited liver disease of childhood which is characterized by cholestasis and normal serum gamma-glutamyltransferase activity. Defects in ABCB11 are also found in cases of chronic intrahepatic cholestasis without obvious familial history of chronic liver disease.
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分子量
- 146407
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基因ID
- 8647
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NCBI登录号
- NP_003733
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UniProt
- O95342
抗原
-
