ABCB11 抗体 (AA 600-750)
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北京 101111
Quick Overview for ABCB11 抗体 (AA 600-750) (ABIN6136348)
抗原
See all ABCB11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-750
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序列
- VLSKIQHGHT IISVAHRLST VRAADTIIGF EHGTAVERGT HEELLERKGV YFTLVTLQSQ GNQALNEEDI KDATEDDMLA RTFSRGSYQD SLRASIRQRS KSQLSYLVHE PPLAVVDHKS TYEEDRKDKD IPVQEEVEPA PVRRILKFSA P
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human ABCB11 (NP_003733.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
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别名
- ABCB11
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背景
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.,ABCB11,ABC16,BRIC2,BSEP,PFIC-2,PFIC2,PGY4,SPGP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ABCB11
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分子量
- 146 kDa
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基因ID
- 8647
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UniProt
- O95342
抗原
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