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ABCB11 抗体 (C-Term)

The 兔 多克隆 anti-ABCB11 antibody is suitable to detect ABCB11 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC 和 IF.
产品编号 ABIN3043733
发货至: 中国
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Quick Overview for ABCB11 抗体 (C-Term) (ABIN3043733)

抗原

See all ABCB11 抗体
ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

适用

  • 25
  • 9
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 25
  • 4

克隆类型

  • 24
  • 5
多克隆

标记

  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ABCB11 antibody is un-conjugated

应用范围

  • 14
  • 11
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1175-1199, C-Term

    原理

    Anti-ABCB11 Antibody

    序列

    KYGDNTKEIP MERVIAAAKQ AQLHD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ABCB11 Antibody (ABIN3043733). Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB11, different from the related mouse and rat sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunofluorescence, 2 μg/mL, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

    别名

    ABCB11

    背景

    Synonyms: Bile salt export pump,ATP-binding cassette sub-family B member 11,ABCB11,BSEP,

    Tissue Specificity: Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.

    Background: Bile Salt Export Pump (BSEP) is a protein which in humans is encoded by the ABCB 11 gene. It is a member of the superfamily of ATP-binding cassette (ABC) transporters, also known as ABCB11. It is mapped to chromosome 2q24. The BSEP protein is mainly expressed in the liver. ABCB11 is a gene associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) which caused by mutations in the ABCB11 gene will increases the risk of hepatocellular carcinoma in early life.

    Sequence Similarities: Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

    分子量

    146 kDa

    基因ID

    8647

    UniProt

    O95342
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