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MDM2 抗体 (AA 26-169)

MDM2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3C1E3 unconjugated
产品编号 ABIN7193584
发货至: 中国
  • 抗原 See all MDM2 抗体
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    抗原表位
    • 25
    • 25
    • 10
    • 10
    • 10
    • 10
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    AA 26-169
    适用
    • 176
    • 69
    • 49
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 151
    • 27
    • 1
    小鼠
    克隆类型
    • 150
    • 29
    单克隆
    标记
    • 100
    • 10
    • 8
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    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MDM2 antibody is un-conjugated
    应用范围
    • 120
    • 74
    • 57
    • 38
    • 28
    • 27
    • 27
    • 19
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    • 16
    • 11
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    • 1
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    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    MDM2 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. Coli.
    克隆位点
    3C1E3
    亚型
    IgG2b
    Top Product
    Discover our top product MDM2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200-1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    别名
    MDM2 (MDM2 产品)
    背景

    Description:

    This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

    Aliases: HDMX, LSKB, hdm2, ACTFS

    分子量
    55.2kDa
    基因ID
    4193
    UniProt
    Q00987
    途径
    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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