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- 抗原 See all ARHGEF18 抗体
- ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
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抗原表位
- AA 159-551
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF18 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Rho guanine nucleotide exchange factor 18 protein (159-551AA)
- 亚型
- IgG
- Top Product
- Discover our top product ARHGEF18 Primary Antibody
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anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (Center) antibody
ARHGEF18 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 159-551) antibodyARHGEF18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 1-89) antibodyARHGEF18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 8H6 unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (C-Term) antibodyVerified ARHGEF18 适用: 人 ELISA, WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibodyARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (HRP)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (FITC)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (Biotin)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
- 别名
- ARHGEF18 (ARHGEF18 产品)
- 别名
- arhgef18 antibody, wu:fc21e04 antibody, wu:fj05f11 antibody, zgc:85686 antibody, P114-RhoGEF antibody, AI467246 antibody, D030053O22Rik antibody, rho/rac guanine nucleotide exchange factor (GEF) 18a antibody, Rho/Rac guanine nucleotide exchange factor (GEF) 18 antibody, Rho/Rac guanine nucleotide exchange factor 18 antibody, rho guanine nucleotide exchange factor 18 antibody, rho/rac guanine nucleotide exchange factor (GEF) 18 antibody, arhgef18a antibody, ARHGEF18 antibody, LOC100027283 antibody, Arhgef18 antibody
- 背景
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Background: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.
Aliases: 114 kDa Rho specific guanine nucleotide exchange factor antibody, 114 kDa Rho-specific guanine nucleotide exchange factor antibody, ARHGEF 18 antibody, Arhgef18 antibody, ARHGI_HUMAN antibody, KIAA0521 antibody, MGC15913 antibody, p114 Rho GEF antibody, p114-Rho-GEF antibody, p114RhoGEF antibody, Rho guanine nucleotide exchange factor 18 antibody, Rho specific guanine nucleotide exchange factor p114 antibody, Rho/Rac guanine nucleotide exchange factor (GEF) 18 antibody, Rho/Rac guanine nucleotide exchange factor 18 antibody, SA RhoGEF antibody, SA-RhoGEF antibody, Septin associated RhoGEF antibody, Septin-associated RhoGEF antibody
- UniProt
- Q6ZSZ5
- 途径
- Neurotrophin Signaling Pathway
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