ARHGEF18 产品
(rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
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Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
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Featured ARHGEF18 Categories
ARHGEF18 抗体
High quality antibodies with extensive validation data.
ARHGEF18 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ARHGEF18 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
- (3)
- (2)
Cat. No.
ABIN2855329
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7167972
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN2565349
Quantity
100 μg
Datasheet
Datasheet
Recommended ARHGEF18 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229254
Quantity
96 tests
Datasheet
Datasheet
Recommended ARHGEF18 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345543
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3089154
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3135770
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ARHGEF18 Products
: "Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly." in: Cell reports, Vol. 32, Issue 3, pp. 107924, (2020) (PubMed).: "VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism." in: The Journal of cell biology, Vol. 218, Issue 5, pp. 1725-1742, (2019) (PubMed).
: "Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs." in: eLife, Vol. 7, (2018) (PubMed).
: "Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration." in: The Journal of cell biology, Vol. 216, Issue 6, pp. 1543-1556, (2017) (PubMed).
: "An apical MRCK-driven morphogenetic pathway controls epithelial polarity." in: Nature cell biology, Vol. 19, Issue 9, pp. 1049-1060, (2017) (PubMed).
: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).
: "Expression of p114RhoGEF predicts lymph node metastasis and poor survival of squamous-cell lung carcinoma patients." in: Tumour biology, Vol. 34, Issue 3, pp. 1925-33, (2013) (PubMed).
: "ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation." in: Development (Cambridge, England), Vol. 140, Issue 13, pp. 2787-97, (2013) (PubMed).
: "Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion." in: PLoS ONE, Vol. 7, Issue 11, pp. e50188, (2012) (PubMed).
: "Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis." in: Nature cell biology, Vol. 13, Issue 2, pp. 159-66, (2011) (PubMed).
Synonyms and alternative names related to ARHGEF18
rho/rac guanine nucleotide exchange factor (GEF) 18a (arhgef18a), Rho/Rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18), Rho/Rac guanine nucleotide exchange factor 18 (ARHGEF18), rho guanine nucleotide exchange factor 18 (LOC100027283), rho/rac guanine nucleotide exchange factor (GEF) 18 (Arhgef18), Rho/Rac guanine nucleotide exchange factor 18 (Arhgef18), AI467246, arhgef18, D030053O22Rik, P114-RhoGEF, wu:fc21e04, wu:fj05f11, zgc:85686Protein level used designations for ARHGEF18
- rho/rac guanine nucleotide exchange factor (GEF) 18
- Rho/Rac guanine nucleotide exchange factor (GEF) 18
- Rho-specific guanine nucleotide exchange factor p114
- 114 kDa Rho-specific guanine nucleotide exchange factor
- P114-RHO-GEF
- Rho/Rac guanine nucleotide exchange factor 18
- SA-RhoGEF
- p114RhoGEF
- rho guanine nucleotide exchange factor 18
- septin-associated RhoGEF
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