ARHGEF18 Protein (AA 159-551, partial) (GST tag)
-
- 抗原 See all ARHGEF18 蛋白
- ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
- 蛋白类型
- Recombinant
- 产品特性
- AA 159-551, partial
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This ARHGEF18 protein is labelled with GST tag.
- 应用范围
- ELISA
- 序列
- MTVSQKGGPQ PTPSPAGPGT QLGPITGEMD EADSAFLKFK QTADDSLSLT SPNTESIFVE DPYTASLRSE IESDGHEFEA ESWSLAVDAA YAKKQKREVV KRQDVLYELM QTEVHHVRTL KIMLKVYSRA LQEELQFSSK AIGRLFPCAD DLLETHSHFL ARLKERRQES LEEGSDRNYV IQKIGDLLVQ QFSGENGERM KEKYGVFCSG HNEAVSHYKL LLQQNKKFQN LIKKIGNFSI VRRLGVQECI LLVTQRITKY PVLVERIIQN TEAGTEDYED LTQALNLIKD IISQVDAKVS ECEKGQRLRE IAGKMDLKSS SKLKNGLTFR KEDMLQRQLH LEGMLCWKTT SGRLKDILAI LLTDVLLLLQ EKDQKYVFAS VDSKPPVISL QKL
- 产品特性
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
- 纯度
- 95 %
- Top Product
- Discover our top product ARHGEF18 蛋白
-
rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 1-89) protein (GST tag)
ARHGEF18 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 1-1173) protein (His tag)Crystallography grade ARHGEF18 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 1-1021) protein (His tag)Crystallography grade ARHGEF18 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
-
- 说明
-
The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 浓度
- 0.2-2 mg/mL
- 缓冲液
- Tris-based buffer, 50 % glycerol
- 注意事项
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
-
- 抗原
- ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
- 别名
- Rho guanine nucleotide exchange factor 18 protein (ARHGEF18 产品)
- 别名
- arhgef18 Protein, wu:fc21e04 Protein, wu:fj05f11 Protein, zgc:85686 Protein, P114-RhoGEF Protein, AI467246 Protein, D030053O22Rik Protein, rho/rac guanine nucleotide exchange factor (GEF) 18a Protein, Rho/Rac guanine nucleotide exchange factor (GEF) 18 Protein, Rho/Rac guanine nucleotide exchange factor 18 Protein, rho guanine nucleotide exchange factor 18 Protein, rho/rac guanine nucleotide exchange factor (GEF) 18 Protein, arhgef18a Protein, ARHGEF18 Protein, LOC100027283 Protein, Arhgef18 Protein
- 背景
- Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.
- 分子量
- 71.9 kD
- UniProt
- Q6ZSZ5
- 途径
- Neurotrophin Signaling Pathway
-
