ARHGEF11 产品
(rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured ARHGEF11 Categories
ARHGEF11 抗体
High quality antibodies with extensive validation data.
ARHGEF11 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ARHGEF11 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN523257
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN961419
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7184414
Quantity
100 μL
Datasheet
Datasheet
Recommended ARHGEF11 蛋白
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Wheat germ
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Cat. No.
ABIN1345537
Quantity
10 μg
Datasheet
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Reactivity
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Source
Tobacco (Nicotiana tabacum)
Validations
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ABIN3089058
Quantity
1 mg
Datasheet
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HEK-293 Cells
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Cat. No.
ABIN2714890
Quantity
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Datasheet
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Latest Publications for our ARHGEF11 Products
: "PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 10, pp. 1045-1058, (2019) (PubMed).: "Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation." in: Nature cell biology, Vol. 17, Issue 4, pp. 397-408, (2015) (PubMed).
: "Allelic Variants in Arhgef11 via the Rho-Rock Pathway Are Linked to Epithelial-Mesenchymal Transition and Contributes to Kidney Injury in the Dahl Salt-Sensitive Rat." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132553, (2015) (PubMed).
: "Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models." in: Oncogene, Vol. 31, Issue 16, pp. 2075-89, (2012) (PubMed).
Synonyms and alternative names related to ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11 (arhgef11), Rho guanine nucleotide exchange factor 11 (ARHGEF11), Rho guanine nucleotide exchange factor (GEF) 11 (Arhgef11), Rho guanine nucleotide exchange factor 11 (Arhgef11), rho guanine nucleotide exchange factor 11 (LOC511220), ARHGEF11, B930073M02, E130307F09, GTRAP48, Gtrap48, mKIAA0380, PDZ-RHOGEF, PDZ-RhoGEF, Prg, RhoGEFProtein level used designations for ARHGEF11
- PDZ-RhoGEF
- rho guanine nucleotide exchange factor 11
- Rho guanine nucleotide exchange factor (GEF) 11
- rho guanine nucleotide exchange factor 11-like
- Rho guanine exchange factor (GEF) 11
- RhoA-specific guanine nucleotide exchange factor
- RhoGEF glutamate transport modulator
- glutamate transporter EAAT4-associated protein 48
- RhoGEF glutamate transport modulator GTRAP48
- glutamate transporter EAAT4 associated protein 48
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