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XRCC3 抗体 (AA 1-316)

XRCC3 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7349833
发货至: 中国
  • 抗原 See all XRCC3 抗体
    XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
    抗原表位
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-316
    适用
    • 41
    • 13
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 37
    • 6
    克隆类型
    • 38
    • 5
    多克隆
    标记
    • 32
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XRCC3 antibody is un-conjugated
    应用范围
    • 26
    • 15
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human DNA repair protein XRCC3 protein (1-316AA)
    亚型
    IgG
    Top Product
    Discover our top product XRCC3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
    别名
    XRCC3 (XRCC3 产品)
    别名
    CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody
    背景

    Background: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment, the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. Involved in HJ resolution and thus in processing HR intermediates late in the DNA repair process, the function may be linked to the CX3 complex and seems to involve GEN1 during mitotic cell cycle progression. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.

    Aliases: CMM6 antibody, DNA repair protein XRCC3 antibody, RAD51 like antibody, X ray repair complementing defective repair in Chinese hamster antibody, X ray repair complementing defective repair in Chinese hamster cells 3 antibody, X ray repair cross complementing protein 3 antibody, X-ray repair cross-complementing protein 3 antibody, XRCC 3 antibody, XRCC3 antibody, XRCC3_HUMAN antibody

    UniProt
    O43542
    途径
    DNA Damage Repair
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