PRKAG1 抗体 (AA 1-331)
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- 抗原 See all PRKAG1 抗体
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
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抗原表位
- AA 1-331
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKAG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human 5\\\'-AMP-activated protein kinase subunit gamma-1 protein (1-331AA)
- 亚型
- IgG
- Top Product
- Discover our top product PRKAG1 Primary Antibody
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anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 230-331) antibody
PRKAG1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7H3E9 unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 70-300) antibodyPRKAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyPRKAG1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 1-247) antibodyPRKAG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (Center) antibodyPRKAG1 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 1-30), (N-Term) antibodyPRKAG1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB31402 unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 5-33), (N-Term) antibodyPRKAG1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyPRKAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (N-Term) antibodyPRKAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyPRKAG1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- 别名
- PRKAG1 (PRKAG1 产品)
- 别名
- MGC68503 antibody, zgc:63896 antibody, wu:fa94d09 antibody, wu:fd12h04 antibody, AMPKG antibody, Prkaac antibody, Prkga1 antibody, AA571379 antibody, BB036179 antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit antibody, protein kinase AMP-activated non-catalytic subunit gamma 1 antibody, prkag1.S antibody, prkag1 antibody, PRKAG1 antibody, Prkag1 antibody
- 背景
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Background: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Aliases: 5' AMP activated protein kinase gamma 1 subunit antibody, 5' AMP activated protein kinase subunit gamma 1 antibody, 5''-AMP-activated protein kinase subunit gamma-1 antibody, AAKG1_HUMAN antibody, AMP activated protein kinase noncatalytic gamma 1 subunit antibody, AMPK gamma 1 chain antibody, AMPK gamma1 antibody, AMPK subunit gamma-1 antibody, AMPKg antibody, MGC8666 antibody, PRKAG 1 antibody, PRKAG1 antibody, Protein kinase AMP activated gamma 1 non catalytic subunit antibody, protein kinase, AMP-activated, noncatalytic gamma-1 antibody
- UniProt
- P54619
- 途径
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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