PRKAG1 抗体 (Center)
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北京 101111
Quick Overview for PRKAG1 抗体 (Center) (ABIN2855115)
抗原
See all PRKAG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 猪, 猕猴, 牛
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交叉反应 （详细）
- Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)
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产品特性
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Rabbit Polyclonal antibody to AMPK gamma 1 (5'-AMP-activated protein kinase subunit gamma-1)
AMPK gamma 1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human AMPK gamma 1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 230-331) antibody
PRKAG1 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7H3E9 unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyPRKAG1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 70-300) antibodyPRKAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 1-247) antibodyPRKAG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 1-331) antibodyPRKAG1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (AA 1-30), (N-Term) antibodyPRKAG1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB31402 unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyKD Validated PRKAG1 适用: 人 WB 宿主: 兔 Monoclonal 25GB2915 unconjugated Recombinant Antibody
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) (N-Term) antibodyPRKAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyPRKAG1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) antibodyPRKAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference Immunoprecipitation Assay-dependent dilution Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunoprecipitationAssay-dependent dilution Western blot1:500-1:3000*
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说明
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Positive Control: mouse liver
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.33 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).
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- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
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别名
- AMPK gamma 1
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背景
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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分子量
- 38 kDa
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基因ID
- 5571
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途径
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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