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- 抗原
- AKT1/3
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抗原表位
- pTyr437
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适用
- 人
-
宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of tyrosine 437 (T-R-Y(p)-F-D) derived from Human AKT1/3.
- 亚型
- IgG
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anti-AKT1/3 (AA 401-479) antibody
适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated
anti-AKT1/3 (pTyr434), (pTyr437) antibody适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1/3 (pTyr437), (Tyr434) antibody适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-AKT1/3 (pTyr434), (pTyr437) antibody适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1/3 (Tyr434), (Tyr437) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AKT1/3 (Lys539) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1/3 (AA 406-455), (pTyr437) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1/3 antibody适用: 人 宿主: 小鼠 Monoclonal AT6D5 unconjugated
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- AKT1/3
- 别名
- AKT1/AKT3
- 背景
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Background: AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling.
Aliases: AKT 1 antibody, AKT antibody, AKT1 antibody, AKT1_HUMAN antibody, C AKT antibody, cAKT antibody, MGC99656 antibody, PKB alpha antibody, PKB antibody, PKB-ALPHA antibody, PRKBA antibody, Protein Kinase B Alpha antibody, Protein kinase B antibody, Proto-oncogene c-Akt antibody, RAC Alpha antibody, RAC antibody, Rac protein kinase alpha antibody, RAC Serine/Threonine Protein Kinase antibody, RAC-alpha serine/threonine-protein kinase antibody, RAC-PK-alpha antibody, v akt murine thymoma viral oncogene homolog 1 antibody, vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody
- UniProt
- P31749
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