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Recombinant ADAM17 抗体

ADAM17 适用: 人 ELISA, IF 宿主: 兔 Monoclonal 5A1 unconjugated Recombinant Antibody
产品编号 ABIN7321717
发货至: 中国
  • 抗原 See all ADAM17 抗体
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    抗体类型
    Recombinant Antibody
    适用
    • 104
    • 52
    • 50
    • 4
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    • 4
    • 1
    宿主
    • 89
    • 13
    • 2
    • 1
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    克隆类型
    • 82
    • 24
    单克隆
    标记
    • 48
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    This ADAM17 antibody is un-conjugated
    应用范围
    • 78
    • 47
    • 38
    • 15
    • 14
    • 13
    • 10
    • 10
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    • 4
    • 4
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    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human ADAM17
    克隆位点
    5A1
    亚型
    IgG
    Top Product
    Discover our top product ADAM17 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    别名
    ADAM17 (ADAM17 产品)
    别名
    ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
    背景

    Background: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.

    Aliases: Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b), ADAM17, CSVP TACE

    UniProt
    P78536
    途径
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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