ERK2 抗体
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- 抗原 See all ERK2 (MAPK1) 抗体
- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ERK2 antibody is un-conjugated
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应用范围
- ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- 特异性
- Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely-related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein coupled receptor ligands and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK 1 and ERK 2 requires phosphorylation by upstream kinases such as MAP kinase (MEK), MEK kinase and Raf-1. ERK 1 and ERK 2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the threonine-glutamate-tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human MAPK1 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product MAPK1 Primary Antibody
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anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibody
MAPK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 25-360) antibodyMAPK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 261-360) antibodyMAPK1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 6F8 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 9E9 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9H1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibodyMAPK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (N-Term) antibodyMAPK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 310-360) antibodyMAPK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (0.5-2 μg/million cells), Immunofluorescence (0.5-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
- 别名
- MAPK1 (MAPK1 产品)
- 别名
- ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, 9030612K14Rik antibody, AA407128 antibody, AU018647 antibody, C78273 antibody, Erk2 antibody, Prkm1 antibody, p42mapk antibody, zERK2 antibody, MAPK1 antibody, Xp42 antibody, erk antibody, erk2 antibody, ert1 antibody, mapk antibody, mapk1b antibody, mapk2 antibody, mpk1 antibody, prkm1 antibody, prkm2 antibody, mapk1 antibody, mapk1a antibody, xp42 antibody, ATMPK1 antibody, F14N23.9 antibody, F14N23_9 antibody, MITOGEN-ACTIVATED PROTEIN KINASE antibody, mitogen-activated protein kinase 1 antibody, MNK1 antibody, ATMPK2 antibody, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antibody, T30E16.13 antibody, T30E16_13 antibody, mitogen-activated protein kinase homolog 2 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 1 antibody, mitogen activated protein kinase 1 antibody, mitogen-activated protein kinase 1 L homeolog antibody, mitogen-activated protein kinase 1 S homeolog antibody, mitogen activated protein kinase 3 antibody, mitogen-activated protein kinase homolog 2 antibody, MAPK3 antibody, Mapk3 antibody, MAPK1 antibody, Mapk1 antibody, mapk1 antibody, mapk1.L antibody, mapk1.S antibody, PfMAP1 antibody, MPK1 antibody, PVX_084965 antibody, LOC9328617 antibody, Tsp_01601 antibody, MPK2 antibody
- 背景
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Extracellular Signal Regulated Kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, Mapk1, MAPK2, P38, P40, P41, p42-MAPK, PRKM1, PRKM2, protein kinase, mitogen-activated, 1 / 2, protein tyrosine kinase ERK2, ERT1,MAPK1 / ERK2 (Transcription Factor)
Cellular localisation: Nucleus. - 分子量
- 41.3kDa
- 基因ID
- 5594, 431850
- UniProt
- P28482
- 途径
- MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins
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