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NAC1 抗体

NACC1 适用: 人 FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126218
发货至: 中国
  • 抗原 See all NAC1 (NACC1) 抗体
    NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
    适用
    • 30
    • 28
    • 18
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 38
    • 8
    • 1
    小鼠
    克隆类型
    • 39
    • 8
    单克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAC1 antibody is un-conjugated
    应用范围
    • 33
    • 13
    • 13
    • 10
    • 7
    • 5
    • 3
    • 1
    Flow Cytometry (FACS)
    特异性
    The BTB (broad-complex, tramtrack and bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
    交叉反应 (详细)
    Human
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human NACC1 protein
    亚型
    IgG2a
    Top Product
    Discover our top product NACC1 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, MCF7 or K562 cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
    别名
    NACC1 (NACC1 产品)
    别名
    BEND8 antibody, BTBD14B antibody, BTBD30 antibody, NAC-1 antibody, NAC1 antibody, NACC1 antibody, 2010001H03Rik antibody, 4930511N13Rik antibody, Btbd14b antibody, Nac1 antibody, Nac-1 antibody, nucleus accumbens associated 1 antibody, nucleus accumbens associated 1, BEN and BTB (POZ) domain containing antibody, NACC1 antibody, Nacc1 antibody
    背景
    BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, NAC-1, NAC1, Nucleus accumbens-associated protein 1,NACC1 / Nac1 / BTBD14B
    Cellular localisation: Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation.
    分子量
    57kDa
    基因ID
    112939, 531614
    UniProt
    Q96RE7
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