NAC1 抗体
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- 抗原 See all NAC1 (NACC1) 抗体
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NAC1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The BTB (broad-complex, tramtrack and bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
- 交叉反应 (详细)
- Human
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human NACC1 protein
- 亚型
- IgG2a
- Top Product
- Discover our top product NACC1 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, MCF7 or K562 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
- 别名
- NACC1 (NACC1 产品)
- 别名
- BEND8 antibody, BTBD14B antibody, BTBD30 antibody, NAC-1 antibody, NAC1 antibody, NACC1 antibody, 2010001H03Rik antibody, 4930511N13Rik antibody, Btbd14b antibody, Nac1 antibody, Nac-1 antibody, nucleus accumbens associated 1 antibody, nucleus accumbens associated 1, BEN and BTB (POZ) domain containing antibody, NACC1 antibody, Nacc1 antibody
- 背景
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BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, NAC-1, NAC1, Nucleus accumbens-associated protein 1,NACC1 / Nac1 / BTBD14B
Cellular localisation: Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation. - 分子量
- 57kDa
- 基因ID
- 112939, 531614
- UniProt
- Q96RE7
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