NAC1 抗体
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- 抗原 See all NAC1 (NACC1) 抗体
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Peptide sequence around aa.519~523(A-G-P-S-A) derived from Human NAC1
- 亚型
- IgG
- Top Product
- Discover our top product NACC1 Primary Antibody
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
- 别名
- NACC1 (NACC1 产品)
- 别名
- BEND8 antibody, BTBD14B antibody, BTBD30 antibody, NAC-1 antibody, NAC1 antibody, NACC1 antibody, 2010001H03Rik antibody, 4930511N13Rik antibody, Btbd14b antibody, Nac1 antibody, Nac-1 antibody, nucleus accumbens associated 1 antibody, nucleus accumbens associated 1, BEN and BTB (POZ) domain containing antibody, NACC1 antibody, Nacc1 antibody
- 背景
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Background:
Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival."
Nakayama K., Nakayama N., Davidson B.,et al.
Proc. Natl. Acad. Sci. U.S.A. 103:18739-18744(2006) "NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor."
Nakayama K., Nakayama N., Wang T.-L., Shih I.-M. Cancer Res. 67:8058-8064(2007)Aliases: BEND8 antibody; BTB Domain Containing 14B antibody; BTB/POZ domain-containing protein 14B antibody; btbd14b antibody; FLJ37383 antibody; NAC-1 antibody; NAC1 antibody; Nacc1 antibody; NACC1_HUMAN antibody; Nucleus accumbens-associated protein 1 antibody
- UniProt
- Q96RE7
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