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Collagen IV 抗体 (AA 1571-1669)

COL4 适用: 人, 小鼠, 大鼠, Pig ELISA, WB, IHC (fro), IHC (p), FACS, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN707396
发货至: 中国
  • 抗原 See all Collagen IV (COL4) 抗体
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    抗原表位
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1571-1669
    适用
    • 90
    • 42
    • 40
    • 22
    • 16
    • 11
    • 5
    • 2
    人, 小鼠, 大鼠, Pig
    宿主
    • 59
    • 27
    • 13
    克隆类型
    • 71
    • 28
    多克隆
    标记
    • 49
    • 10
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Collagen IV antibody is un-conjugated
    应用范围
    • 61
    • 49
    • 30
    • 28
    • 27
    • 26
    • 25
    • 25
    • 20
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, Pig, 大鼠
    预测反应
    Dog,Cow,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Collagen alpha-1(IV) chain
    亚型
    IgG
    Top Product
    Discover our top product COL4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Sato, Coburn: "Leptospira interrogans causes quantitative and morphological disturbances in adherens junctions and other biological groups of proteins in human endothelial cells." in: PLoS neglected tropical diseases, Vol. 11, Issue 7, pp. e0005830, (2017) (PubMed).

    Wu, Zhang, Ma, Zhang, Qin: "The effect of resveratrol on FoxO1 expression in kidneys of diabetic nephropathy rats." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9085-93, (2012) (PubMed).

  • 抗原
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    别名
    Collagen 4 (COL4 产品)
    别名
    collagen, type IV antibody, Let-2 antibody
    背景

    Synonyms: ICH, HANAC, POREN1, arresten, Collagen alpha-1(IV) chain, COL4A1

    Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

    基因ID
    1282
    UniProt
    P02462
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