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Collagen IV 抗体

This 山羊 多克隆 antibody specifically detects Collagen IV in WB, ELISA, IHC (fro), IHC (p), FACS, IP, ICC 和 IEM. It exhibits reactivity toward 人, 小鼠, 大鼠, Pig, 兔, 小鸡, Chinchilla chinchilla, 犬, 豚鼠, 马, Japanese macaque (Macaca fuscata), 绵羊 和 Tree shrew. It has been mentioned in 21+ publications
产品编号 ABIN135052
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Collagen IV 抗体 (ABIN135052)

抗原

See all Collagen IV (COL4) 抗体
Collagen IV (COL4) (Collagen, Type IV (COL4))

适用

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人, 小鼠, 大鼠, Pig, 兔, 小鸡, Chinchilla chinchilla, 犬, 豚鼠, 马, Japanese macaque (Macaca fuscata), 绵羊, Tree shrew

宿主

  • 70
  • 33
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山羊

克隆类型

  • 73
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多克隆

标记

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This Collagen IV antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)
  • 原理

    Goat Anti-Type IV Collagen-UNLB

    特异性

    Reacts with conformational determinants on type IV collagen Referenced species reactivities include - Human 1,12,14,27,29,31,34,36 Chicken 5,13,15 Porcine 11,22,25 Mouse 4,5,7,8,30,32 Chinchilla 17 Rabbit 5,6,14,20,23 Rat 2,3,10,26,27,33,35 Equine 18,28 Sheep 24 Bovine 5,24 Guinea Pig 14 Tree Shrew 21 Canine 9,19 Japanese Macaque 16

    交叉反应 (详细)

    Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

    产品特性

    Purified Anti-Type IV Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, western blotting, and immunoprecipitation assays.

    纯化方法

    Purified by affinity chromatography on type IV collagen covalently linked to agarose, cross-adsorbed against Collagen types I, II, III, V, and VI for minimal reactivity

    免疫原

    Type IV collagen

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Pooled antisera from goats hyperimmunized with type IV collagen

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.4 mg/mL

    缓冲液

    Borate buffered saline, pH 8.2

    储存条件

    4 °C

    储存方法

    2-8°C
  • Tonello, Lee, Berta: "Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice." in: The journal of pain : official journal of the American Pain Society, Vol. 20, Issue 5, pp. 515-527, (2020) (PubMed).

    Zaitoun, Cikla, Zafer, Udho, Almomani, Suscha, Cengiz, Sorenson, Sheibani: "Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy." in: Scientific reports, Vol. 8, Issue 1, pp. 9166, (2019) (PubMed).

    Singh, Houng, Reed: "Matrix Metalloproteinase-9 Mediates the Deleterious Effects of α2-Antiplasmin on Blood-Brain Barrier Breakdown and Ischemic Brain Injury in Experimental Stroke." in: Neuroscience, Vol. 376, pp. 40-47, (2019) (PubMed).

    Fisslthaler, Zippel, Abdel Malik, Delgado Lagos, Zukunft, Thoele, Siuda, Soehnlein, Wittig, Heidler, Weigert, Fleming: "Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis." in: International journal of molecular sciences, Vol. 20, Issue 12, (2019) (PubMed).

    Dias, Kim, Holl, Werne Solnestam, Lundeberg, Carlén, Göritz, Frisén: "Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury." in: Cell, Vol. 173, Issue 1, pp. 153-165.e22, (2019) (PubMed).

    Ellenbroek, de Haan, van Klarenbosch, Brans, van de Weg, Smeets, de Jong, Arslan, Timmers, Goumans, Hoefer, Doevendans, Pasterkamp, Meyaard, de Jager: "Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 18039, (2019) (PubMed).

    Hu, Dziumbla, Lin, Bibli, Zukunft, de Mos, Awwad, Frömel, Jungmann, Devraj, Cheng, Wang, Fauser, Eberhart, Sodhi, Hammock, Liebner, Müller, Glaubitz, Hammes, Popp, Fleming: "Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy." in: Nature, Vol. 552, Issue 7684, pp. 248-252, (2018) (PubMed).

    Mao, Kiss, Ou, Gould: "Genetic dissection of anterior segment dysgenesis caused by a Col4a1 mutation in mouse." in: Disease models & mechanisms, Vol. 10, Issue 4, pp. 475-485, (2017) (PubMed).

    Friedrich, Bederson, Sehba: "Gender influences the initial impact of subarachnoid hemorrhage: an experimental investigation." in: PLoS ONE, Vol. 8, Issue 11, pp. e80101, (2015) (PubMed).

    Chen, Advani, Thai, Kabir, Sood, Gibson, Yuen, Connelly, Marsden, Kelly, Gilbert, Advani: "SDF-1/CXCR4 Signaling Preserves Microvascular Integrity and Renal Function in Chronic Kidney Disease." in: PLoS ONE, Vol. 9, Issue 3, pp. e92227, (2014) (PubMed).

    Mao-Ying, Kavelaars, Krukowski, Huo, Zhou, Price, Cleeland, Heijnen: "The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model." in: PLoS ONE, Vol. 9, Issue 6, pp. e100701, (2014) (PubMed).

    Wu, Davis, McMillen, Schaeffer, Zhou, Qi, Mazandarani, Alialy, Hudkins, Lusis, LeBoeuf: "Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation." in: Physiological reports, Vol. 2, Issue 11, (2014) (PubMed).

    Abrahamson, St John, Stroganova, Zelenchuk, Steenhard: "Laminin and type IV collagen isoform substitutions occur in temporally and spatially distinct patterns in developing kidney glomerular basement membranes." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 10, pp. 706-18, (2013) (PubMed).

    Maggi, Ericson, Mascarelli, Bradley, Breitschwerdt: "Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure." in: Parasites & vectors, Vol. 6, pp. 101, (2013) (PubMed).

    Mirmalek-Sani, Orlando, McQuilling, Pareta, Mack, Salvatori, Farney, Stratta, Atala, Opara, Soker: "Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering." in: Biomaterials, Vol. 34, Issue 22, pp. 5488-95, (2013) (PubMed).

    Manigrasso, Sawyer, Hutchens, Flynn, Maric-Bilkan: "Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats." in: American journal of physiology. Renal physiology, (2012) (PubMed).

    Manigrasso, Sawyer, Marbury, Flynn, Maric: "Inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induced diabetic rats." in: American journal of physiology. Renal physiology, Vol. 301, Issue 3, pp. F634-40, (2011) (PubMed).

    Boyette-Davis, Cata, Zhang, Driver, Wendelschafer-Crabb, Kennedy, Dougherty: "Follow-up psychophysical studies in bortezomib-related chemoneuropathy patients." in: The journal of pain : official journal of the American Pain Society, Vol. 12, Issue 9, pp. 1017-24, (2011) (PubMed).

    Liu, Chen, Huang, Chung, Zhou, Fu, Szalai, Lan: "C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes." in: Diabetologia, Vol. 54, Issue 10, pp. 2713-23, (2011) (PubMed).

    Glorieux, Bachert, Favoreel, Vandekerckhove, Steukers, Rekecki, Van den Broeck, Goossens, Croubels, Clayton, Nauwynck: "Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa." in: PLoS ONE, Vol. 6, Issue 7, pp. e22160, (2011) (PubMed).

  • 抗原

    Collagen IV (COL4) (Collagen, Type IV (COL4))

    别名

    TypeIV Collagen

    背景

    Description: Goat Anti-Type IV Collagen-UNLB

    NCBI_Official_Symbol: COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6

    Synoynms: COL4

    基因ID

    1282, 1284, 1285

    UniProt

    P02462
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