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MCM2 抗体 (AA 591-904)

This anti-MCM2 antibody is a 兔 多克隆 antibody detecting MCM2 in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116309
发货至: 中国

Quick Overview for MCM2 抗体 (AA 591-904) (ABIN7116309)

抗原

See all MCM2 抗体
MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MCM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 抗原表位

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    AA 591-904

    原理

    MCM2 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 591-904aa

    Immunogen: minichromosome maintenance complex component 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

    别名

    MCM2

    背景

    Synonyms: DNA replication licensing factor MCM2|Minichromosome maintenance protein 2 homolog|Nuclear protein BM28|MCM2|BM28|CCNL1|CDCL1|KIAA0030

    Background: Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

    分子量

    116-125 kDa

    基因ID

    4171

    UniProt

    P49736

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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