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MCM2 抗体 (C-Term)

MCM2 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044242
发货至: 中国
  • 抗原 See all MCM2 抗体
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    抗原表位
    • 19
    • 17
    • 16
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 889-904, C-Term
    适用
    • 125
    • 71
    • 21
    • 10
    • 10
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 大鼠
    宿主
    • 128
    • 12
    • 2
    • 1
    克隆类型
    • 118
    • 25
    多克隆
    标记
    • 78
    • 9
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This MCM2 antibody is un-conjugated
    应用范围
    • 88
    • 52
    • 52
    • 28
    • 26
    • 26
    • 25
    • 24
    • 12
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    原理
    Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM2(MCM2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    序列
    NKFSHDLKRK MILQQF
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM2(MCM2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: minichromosome maintenance complex component 2
    Protein Name: DNA replication licensing factor MCM2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human MCM2(889-904aa NKFSHDLKRKMILQQF), different from the related rat and mouse sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MCM2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
    别名
    MCM2 (MCM2 产品)
    别名
    CG7538 antibody, DmMCM2 antibody, DmMcm2 antibody, DmeMCM2 antibody, Dmel\\CG7538 antibody, MCM2 antibody, MCM2-7 antibody, MCM2_DROME antibody, McM2 antibody, PCR3 antibody, dMCM2 antibody, l(3)rL074 antibody, XMcm2 antibody, bm28 antibody, ccnl1 antibody, cdc19 antibody, cdcl1 antibody, mitotin antibody, cb737 antibody, chunp6905 antibody, BM28 antibody, CCNL1 antibody, CDCL1 antibody, D3S3194 antibody, MITOTIN antibody, MCM7 antibody, AA959861 antibody, AW476101 antibody, Mcmd2 antibody, mKIAA0030 antibody, Minichromosome maintenance 2 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 2 L homeolog antibody, Mcm2 antibody, mcm2 antibody, MCM2 antibody, mcm2.L antibody
    背景
    MCM2(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 2),also known as MITOTIN, CDCL1 or BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division. And it is similar to members of the family of early S-phase proteins. The MCM2 gene is mapped to 3q21.3. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex(pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. In the G0 stage, the MCM2 and MCM5 proteins were much less abundant than the MCM7 and MCM3 proteins, which suggests that the MCM proteins are not present in stoichiometric amounts and that only a proportion of these molecules actively participate in cell cycle regulation as part of MCM complexes.

    Synonyms: BM28 antibody|CCNL 1 antibody|CCNL1 antibody|CDC like 1 antibody|CDC like-1 antibody|cdc19 antibody|CDCL 1 antibody|CDCL1 antibody|Cell devision cycle like 1 antibody|Cyclin like 1 antibody|cyclin like-1 antibody|D3S3194 antibody|DNA replication licensing factor MCM2 antibody|KIAA0030 antibody|MCM 2 antibody|MCM2 antibody|MCM2 minichromosome maintenance deficient 2 mitotin antibody|MCM2 minichromosome maintenance deficient 2 mitotin(S. cerevisiae) antibody|MCM2 minichromosome maintenance deficient 2, mitotin antibody|MCM2_HUMAN antibody|MGC10606 antibody|Minichromosome maintenance complex component 2 antibody|Minichromosome maintenance deficient 2(mitotin) antibody|Minichromosome maintenance deficient 2 mitotin antibody|Minichromosome maintenance protein 2 antibody|Minichromosome maintenance protein 2 homolog antibody|Mitotin antibody|Nuclear protein BM28 antibody|OTTHUMP00000216047 antibody|OTTHUMP00000216050 antibody
    UniProt
    P49736
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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