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- 抗原 See all TOP3A 抗体
- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TOP3A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Affinity purification
- 免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse Topoisomerase III alpha
- Top Product
- Discover our top product TOP3A Primary Antibody
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anti-Topoisomerase (DNA) III alpha (TOP3A) (C-Term) antibody
TOP3A 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) (Internal Region) antibodyTOP3A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) antibodyTOP3A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) (AA 1-100) antibodyTOP3A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III alpha (TOP3A) (Center) antibodyTOP3A 适用: 人, Cow, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB (H) 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
- 别名
- Topoisomerase III alpha (TOP3A 产品)
- 别名
- TOP3 antibody, DNA topoisomerase III alpha antibody, topoisomerase (DNA) III alpha antibody, Top3a antibody, TOP3A antibody
- 背景
- DNA topoisomerase 3-alpha (TOP3A) is an essential component of the RMI complex, a complex involves in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. It releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils.
- 分子量
- 112 kDa
- 基因ID
- 21975
- NCBI登录号
- NP_033436
- UniProt
- O70157
- 途径
- DNA Damage Repair
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